RNAseq reveals hydrophobins that are involved in the adaptation of Aspergillus nidulans to lignocellulose.

ABSTRACT:

Background

Sugarcane is one of the world's most profitable crops. Waste steam-exploded sugarcane bagasse (SEB) is a cheap, abundant, and renewable lignocellulosic feedstock for the next-generation biofuels. In nature, fungi seldom exist as planktonic cells, similar to those found in the nutrient-rich environment created within an industrial fermenter. Instead, fungi predominantly form biofilms that allow them to thrive in hostile environments.

Results

In turn, we adopted an RNA-sequencing approach to interrogate how the model fungus, Aspergillus nidulans, adapts to SEB, revealing the induction of carbon starvation responses and the lignocellulolytic machinery, in addition to morphological adaptations. Genetic analyses showed the importance of hydrophobins for growth on SEB.

SUBMITTER: Brown NA 

PROVIDER: S-EPMC4950808 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature