Single- and Bayesian Multi-Marker Genome-Wide Association for Haematological Parameters in Pigs.

ABSTRACT: Haematological traits are important traits that show associations with immune and metabolic status, as well as diseases in humans and animals. Mapping genome regions that affect the blood cell traits can contribute to the identification of genomic features useable as biomarkers for immune, disease and metabolic status. A genome-wide association study (GWAS) was conducted using PorcineSNP60 BeadChips. Single-marker and Bayesian multi-marker approaches were integrated to identify genomic regions and corresponding genes overlapping for both methods. GWAS was performed for haematological traits of 591 German Landrace pig. Heritability estimates for haematological traits were medium to high. In total 252 single SNPs associated with 12 haematological traits were identified (NegLog10 of p-value >

SUBMITTER: Ponsuksili S 

PROVIDER: S-EPMC4951017 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature