Comparative Analysis of Secretome Profiles of Manganese(II)-Oxidizing Ascomycete Fungi.

ABSTRACT: Fungal secretomes contain a wide range of hydrolytic and oxidative enzymes, including cellulases, hemicellulases, pectinases, and lignin-degrading accessory enzymes, that synergistically drive litter decomposition in the environment. While secretome studies of model organisms such as Phanerochaete chrysosporium and Aspergillus species have greatly expanded our knowledge of these enzymes, few have extended secretome characterization to environmental isolates or conducted side-by-side comparisons of diverse species. Thus, the mechanisms of carbon degradation by many ubiquitous soil fungi remain poorly understood. Here we use a combination of LC-MS/MS, genomic, and bioinformatic analyses to characterize and compare the protein composition of the secretomes of four recently isolated, cosmopoli

SUBMITTER: Zeiner CA 

PROVIDER: S-EPMC4951024 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature