Application of the Navigation Guide systematic review methodology to the evidence for developmental and reproductive toxicity of triclosan.

ABSTRACT:

Background

There are reports of developmental and reproductive health effects associated with the widely used biocide triclosan.

Objective

Apply the Navigation Guide systematic review methodology to answer the question: Does exposure to triclosan have adverse effects on human development or reproduction?

Methods

We applied the first 3 steps of the Navigation Guide methodology: 1) Specify a study question, 2) Select the evidence, and 3) Rate quality and strength of the evidence. We developed a protocol, conducted a comprehensive search of the literature, and identified relevant studies using pre-specified criteria. We assessed the number and type of all relevant studies. We evaluated each included study for risk of bias and rated the quality and strength of the evidenc

SUBMITTER: Johnson PI 

PROVIDER: S-EPMC4951161 | biostudies-literature | 2016 Jul-Aug

REPOSITORIES: biostudies-literature