RNA expression of TLR10 in normal equine tissues.

ABSTRACT:

Background

Toll like receptors are one of the major innate immune system pathogen recognition systems. There is little data on the expression of the TLR10 member of this family in the horse.

Results

This paper describes the genetic structure of the Equine TLR10 gene and its RNA expression in a range of horse tissues. It describes the phylogenetic analysis of the Equine TLR1,6,10,2 annotations in the horse genome, firmly identifying them in their corresponding gene clades compared to other species and firmly placing the horse gene with other TLR10 genes from odd-toed ungulates. Additional 3' transcript extensions to that annotated for TLR10 in the horse genome have been identified by analysis of RNAseq data. RNA expression of the equine TLR10 gene was highest in peripheral bl

SUBMITTER: Tarlinton RE 

PROVIDER: S-EPMC4952062 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature