Fast frequency-sweep spectroscopic imaging with an ultra-low flip angle.

ABSTRACT: Magnetic resonance (MR) spectroscopic imaging has become an important tool in clinical settings for noninvasively obtaining spatial and metabolic information on a molecular scale. Conventional spectroscopic imaging is acquired in the time domain, and its clinical application is limited by the long acquisition time, restricted spatial coverage, and complex suppression and reconstruction procedures. We introduce a fast MR spectroscopic imaging technique in the frequency domain, termed phase-cycled spectroscopic imaging (PCSI). PCSI uses a balanced steady-state free precession (bSSFP) sequence with an ultra-low flip angle to achieve very high acquisition efficiency with a short repetition time. This approach enables faster frequency sweeping by changing the cycled RF phase and using flexible

SUBMITTER: Guo J 

PROVIDER: S-EPMC4954958 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature