Identification and functional characterization of novel xylose transporters from the cell factories Aspergillus niger and Trichoderma reesei.

ABSTRACT:

Background

Global climate change and fossil fuels limitations have boosted the demand for robust and efficient microbial factories for the manufacturing of bio-based products from renewable feedstocks. In this regard, efforts have been done to enhance the enzyme-secreting ability of lignocellulose-degrading fungi, aiming to improve protein yields while taking advantage of their ability to use lignocellulosic feedstocks. Access to sugars in complex polysaccharides depends not only on their release by specific hydrolytic enzymes, but also on the presence of transporters capable of effectively transporting the constituent sugars into the cell. This study aims to identify and characterize xylose transporters from Aspergillus niger and Trichoderma reesei, two fungi that have been indust

SUBMITTER: Sloothaak J 

PROVIDER: S-EPMC4955148 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature