Accuracy of finite element analyses of CT scans in predictions of vertebral failure patterns under axial compression and anterior flexion.

ABSTRACT: Finite element (FE) models built from quantitative computed tomography (QCT) scans can provide patient-specific estimates of bone strength and fracture risk in the spine. While prior studies demonstrate accurate QCT-based FE predictions of vertebral stiffness and strength, the accuracy of the predicted failure patterns, i.e., the locations where failure occurs within the vertebra and the way in which the vertebra deforms as failure progresses, is less clear. This study used digital volume correlation (DVC) analyses of time-lapse micro-computed tomography (μCT) images acquired during mechanical testing (compression and anterior flexion) of thoracic spine segments (T7-T9, n=28) to measure displacements occurring throughout the T8 vertebral body at the ultimate point. These displacements were

SUBMITTER: Jackman TM 

PROVIDER: S-EPMC4955561 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature