Poor Performance Status Is Associated With Increased Mortality in Patients With Cirrhosis.

ABSTRACT:

Background & aims

Functional status (a patient's ability to perform activities that meet basic needs, fulfill usual roles, and maintain health and well-being) has been linked to outcomes in patients with cirrhosis and can be measured by the Karnofsky performance status (KPS) scale. We investigated the association between KPS score and mortality in patients with cirrhosis.

Methods

We used the United Network for Organ Sharing database to perform a retrospective cohort study of patients listed for liver transplantation in the United States between 2005 and 2015. We used Cox proportional hazards and competing risk regression analyses to examine the association between KPS and mortality and transplantation.

Results

Of 79,092 patients, 44% were in KPS category A (KPS, 80%-1

SUBMITTER: Orman ES 

PROVIDER: S-EPMC4955687 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature