Cost-effectiveness of HIV and syphilis antenatal screening: a modelling study.

ABSTRACT:

Objectives

The WHO called for the elimination of maternal-to-child transmission (MTCT) of HIV and syphilis, a harmonised approach for the improvement of health outcomes for mothers and children. Testing early in pregnancy, treating seropositive pregnant women and preventing syphilis reinfection can prevent MTCT of HIV and syphilis. We assessed the health and economic outcomes of a dual testing strategy in a simulated cohort of 100 000 antenatal care patients in Malawi.

Methods

We compared four screening algorithms: (1) HIV rapid test only, (2) dual HIV and syphilis rapid tests, (3) single rapid tests for HIV and syphilis and (4) HIV rapid and syphilis laboratory tests. We calculated the expected number of adverse pregnancy outcomes, the expected costs and the expected newbor

SUBMITTER: Bristow CC 

PROVIDER: S-EPMC4956558 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature