Survival in HIV-positive transplant recipients compared with transplant candidates and with HIV-negative controls.

ABSTRACT:

Objectives

To evaluate the impact of liver and kidney transplantation on survival in HIV-positive transplant candidates and compare outcomes between HIV-positive and negative recipients.

Design

Observational cohort of HIV-positive transplant candidates and recipients and secondary analysis comparing study recipients to HIV-negative national registry controls.

Methods

We fit proportional hazards models to assess transplantation impact on mortality among recipients and candidates. We compared time to graft failure and death with HIV-negative controls in unmatched, demographic-matched, and risk-adjusted models.

Results

There were 17 (11.3%) and 46 (36.8%) deaths among kidney and liver recipients during a median follow-up of 4.0 and 3.5 years, respectively. Transpl

SUBMITTER: Roland ME 

PROVIDER: S-EPMC4957135 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature