Prevalence and Mimics of Kleine-Levin Syndrome: A Survey in French-Speaking Switzerland.

ABSTRACT:

Study objective

Kleine-Levin syndrome (KLS) is a rare disease of unknown etiology, the diagnosis of which can be challenging. We aimed to estimate KLS prevalence in French-speaking Switzerland, and assess differences with mimicking conditions.

Methods

In this cross-sectional study, KLS patients were identified through a population-based approach, including at our hospital and contacting all sleep-certified facilities and neurologists in French-speaking Switzerland. Furthermore, we identified patients referred to our center for suspected KLS that received other diagnoses. Relevant clinical data of these two groups was compared.

Results

We identified 7 patients with diagnosed KLS (6 since 2009), leading to a prevalence estimation of 3.19 per million (95% confidence inte

SUBMITTER: Habra O 

PROVIDER: S-EPMC4957185 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature