Risk of Malignant Cancer Among Women With New-Onset Atrial Fibrillation.

ABSTRACT:

Importance

A substantial proportion of patients with atrial fibrillation (AF) die of noncardiovascular causes, and recent studies suggest a link between AF and cancer.

Objective

To evaluate the associations between AF and cancer in a large, long-term prospective cohort study.

Design, setting, and participants

In this cohort study, a total of 34 691 women 45 years or older and free of AF, cardiovascular disease, and cancer at baseline were prospectively followed up between 1993 and 2013, for incident AF and malignant cancer within the Women's Health Study, a randomized clinical trial of aspirin and vitamin E for the prevention of cardiovascular disease and cancer. Cox proportional hazards models using time-updated covariates were constructed to assess the association o

SUBMITTER: Conen D 

PROVIDER: S-EPMC4957657 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature