Smoking during pregnancy and ADHD risk: A genetically informed, multiple-rater approach.

ABSTRACT: Maternal smoking during pregnancy (SDP) is a significant public health concern with adverse consequences to the health and well-being of the developing child, including behavioral outcomes such as Attention-Deficit Hyperactivity Disorder (ADHD). There is substantial interest in understanding the nature of this reported association, particularly in light of more recent genetically informed studies that suggest that the SDP-ADHD link is less clear than once thought. In a sample of families (N = 173) specifically selected for sibling pairs discordant for prenatal smoking exposure, we use a sibling-comparison approach that controls for shared genetic and familial influences to assess the effects of SDP on ADHD symptom dimensions. ADHD was measured by both parent and teacher report on the Conne

SUBMITTER: Knopik VS 

PROVIDER: S-EPMC4958030 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature