Association between CD14 SNP -159 C/T and gastric cancer: an independent case-control study and an updated meta-analysis.

ABSTRACT:

Purpose

The association between CD14 -159C/T polymorphism and the susceptibility to gastric cancer (GC) has been reported. However, the results were inconclusive. In the present study, a case-control study and a meta-analysis were performed to assess the possible association between -159C/T in the CD14 gene and GC risk.

Patients and methods

Relevant studies were searched in several databases including PubMed, Web of Science, EMBASE, Chinese National Knowledge Infrastructure database, and Wanfang database (last search was performed on December 30, 2015). In addition, a case-control study involving 164 GC cases and 169 controls was also performed in the analysis. Statistical analysis was performed by the software Revman5.3.

Results

A total of ten published studies and t

SUBMITTER: Gong AM 

PROVIDER: S-EPMC4958350 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature