Associations between scar characteristics by cardiac magnetic resonance and changes in left ventricular ejection fraction in primary prevention defibrillator recipients.

ABSTRACT:

Background

Left ventricular ejection fraction (LVEF) improves over time in 25%-40% of patients with cardiomyopathy with primary prevention implantable cardioverter-defibrillator (ICD). The determinants of LVEF improvement, however, are not well characterized.

Objectives

We sought to examine the associations of clinical risk factors and cardiac imaging markers with changes in LVEF after ICD implantation.

Methods

We conducted a retrospective analysis of cardiac magnetic resonance images in 202 patients who underwent primary prevention ICD implantation to quantify the amount of heterogeneous myocardial tissue (gray zone), dense core, and total scar. LVEF was reassessed at least once after ICD implantation.

Results

Over a mean follow-up of 3 years, LVEF decreased i

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC4958529 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature