Polyphenol compounds and PKC signaling.

ABSTRACT:

Background

Naturally occurring polyphenols found in food sources provide huge health benefits. Several polyphenolic compounds are implicated in the prevention of disease states, such as cancer. One of the mechanisms by which polyphenols exert their biological actions is by interfering in the protein kinase C (PKC) signaling pathways. PKC belongs to a superfamily of serine-threonine kinase and are primarily involved in phosphorylation of target proteins controlling activation and inhibition of many cellular processes directly or indirectly.

Scope of review

Despite the availability of substantial literature data on polyphenols' regulation of PKC, no comprehensive review article is currently available on this subject. This article reviews PKC-polyphenol interactions and its rel

SUBMITTER: Das J 

PROVIDER: S-EPMC4961512 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature