Hemoglobin Concentration and Risk of Incident Stroke in Community-Living Adults.

ABSTRACT:

Background and purpose

In previous observational studies, hemoglobin concentrations have been associated with an increased risk of stroke. However, these studies were limited by a relatively low number of stroke events, making it difficult to determine whether the association of hemoglobin and stroke differed by demographic or clinical factors.

Methods

Using Cox proportional hazards analysis and Kaplan-Meier plots, we examined the association of baseline hemoglobin concentrations with incident stroke in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study, a cohort of black and white adults aged ≥45 years.

Results

A total of 518 participants developed stroke over a mean 7±2 years of follow-up. There was a statistically significant interaction be

SUBMITTER: Panwar B 

PROVIDER: S-EPMC4961542 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature