Pathogenesis and Risk Factors for Cerebral Infarct After Surgical Aortic Valve Replacement.

ABSTRACT:

Background and purpose

Stroke is a potentially devastating complication of cardiac surgery. Identifying predictors of radiographic infarct may lead to improved stroke prevention for surgical patients.

Methods

We reviewed 129 postoperative brain magnetic resonance imagings from a prospective study of patients undergoing surgical aortic valve replacement. Acute infarcts were classified as watershed or embolic using prespecified criteria.

Results

Acute infarct on magnetic resonance imaging was seen in 79 of 129 patients (61%), and interrater reliability for stroke pathogenesis was high (κ=0.93). Embolic infarcts only were identified in 60 patients (46%), watershed only in 2 (2%), and both in 17 (13%). In multivariable logistic regression, embolic infarct was associated w

SUBMITTER: Massaro A 

PROVIDER: S-EPMC4961589 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature