Spot urine sodium measurements do not accurately estimate dietary sodium intake in chronic kidney disease.

ABSTRACT:

Background

Sodium intake influences blood pressure and proteinuria, yet the impact on long-term outcomes is uncertain in chronic kidney disease (CKD). Accurate assessment is essential for clinical and public policy recommendations, but few large-scale studies use 24-h urine collections. Recent studies that used spot urine sodium and associated estimating equations suggest that they may provide a suitable alternative, but their accuracy in patients with CKD is unknown.

Objective

We compared the accuracy of 4 equations [the Nerbass, INTERSALT (International Cooperative Study on Salt, Other Factors, and Blood Pressure), Tanaka, and Kawasaki equations] that use spot urine sodium to estimate 24-h sodium excretion in patients with moderate to advanced CKD.

Design

We evaluat

SUBMITTER: Dougher CE 

PROVIDER: S-EPMC4962156 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature