Energy expenditure and body composition changes after an isocaloric ketogenic diet in overweight and obese men.

ABSTRACT:

Background

The carbohydrate-insulin model of obesity posits that habitual consumption of a high-carbohydrate diet sequesters fat within adipose tissue because of hyperinsulinemia and results in adaptive suppression of energy expenditure (EE). Therefore, isocaloric exchange of dietary carbohydrate for fat is predicted to result in increased EE, increased fat oxidation, and loss of body fat. In contrast, a more conventional view that "a calorie is a calorie" predicts that isocaloric variations in dietary carbohydrate and fat will have no physiologically important effects on EE or body fat.

Objective

We investigated whether an isocaloric low-carbohydrate ketogenic diet (KD) is associated with changes in EE, respiratory quotient (RQ), and body composition.

Design

Seventee

SUBMITTER: Hall KD 

PROVIDER: S-EPMC4962163 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature