Curative Resection of Adrenocortical Carcinoma: Rates and Patterns of Postoperative Recurrence.

ABSTRACT:

Background

Adrenocortical carcinoma (ACC) is a rare malignancy. The aim of this study was to determine the incidence and patterns of recurrence after curative-intent surgery for ACC.

Methods

Patients who underwent curative-intent resection for ACC between 1993 and 2014 were identified from 13 academic institutions participating in the United States ACC study group. Patients with metastasis or an R2 margin were excluded. Patterns and rates of recurrence were determined and classified as locoregional and distant recurrence.

Results

A total of 180 patients with a median age of 52 years (interquartile range 43-61) were identified. Most patients underwent open surgery (n = 111, 64.5 %) and had an R0 resection margin (n = 117, 75.0 %). At last follow-up, 116 patients (64.4

SUBMITTER: Amini N 

PROVIDER: S-EPMC4962540 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature