Interactive effects of physical fitness and body mass index on risk of stroke: A national cohort study.

ABSTRACT:

Background

High body mass index (BMI) and low physical fitness are risk factors for stroke, but their interactive effects are unknown. Elucidation of interactions between these modifiable risk factors can help inform preventive interventions in susceptible subgroups.

Methods

National cohort study of all 1,547,294 military conscripts in Sweden during 1969-1997 (97-98% of all 18-year-old males). Standardized aerobic capacity, muscular strength, and body mass index measurements were examined in relation to stroke identified from inpatient and outpatient diagnoses through 2012 (maximum age 62 years).

Results

Sixteen thousand nine hundred seventy-nine men were diagnosed with stroke in 39.7 million person-years of follow-up. High body mass index, low aerobic fitness, and (l

SUBMITTER: Crump C 

PROVIDER: S-EPMC4963281 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature