Polymorphism in phenobarbital: discovery of a new polymorph and crystal structure of elusive form V.

ABSTRACT: This report highlights the discovery of a new polymorph of the anticonvulsant drug phenobarbital (PB) using polymer-induced heteronucleation (PIHn) and unravelling the crystal structure of the elusive form V. Both forms are characterized by structural, thermal and VT-Raman spectroscopy methods to elucidate phase transformation behavior and shed light on stability relationships.

SUBMITTER: Roy S 

PROVIDER: S-EPMC4964875 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature