Gene Expression Profile in the Liver of Sheep Infected with Cystic Echinococcosis.

ABSTRACT:

Background

Cystic Echinococcosis (CE), caused by infection with the Echinococcus granulosus (E. granulosus), represents considerable health problems in both humans and livestock. Nevertheless, the genetic program that regulates the host response to E. granulosus infection is largely unknown. Previously, using microarray analysis, we found that the innate immunity played a vital role in the E. granulosus defense of the intestine tissue where E. granulosus first invaded. Subsequently, we turned our attention to investigating the molecular immune mechanism in its organ target, the liver, which is where the E. granulosus metacestodes are established and live for very long periods. In this work, the microarray-based methodology was used to study gene expression profiles in the liver of

SUBMITTER: Hui W 

PROVIDER: S-EPMC4965101 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature