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Herpes Simplex Virus-1 Encephalitis in Adults: Pathophysiology, Diagnosis, and Management.


ABSTRACT: Herpetic infections have plagued humanity for thousands of years, but only recently have advances in antiviral medications and supportive treatments equipped physicians to combat the most severe manifestations of disease. Prompt recognition and treatment can be life-saving in the care of patients with herpes simplex-1 virus encephalitis, the most commonly identified cause of sporadic encephalitis worldwide. Clinicians should be able to recognize the clinical signs and symptoms of the infection and familiarize themselves with a rational diagnostic approach and therapeutic modalities, as early recognition and treatment are key to improving outcomes. Clinicians should also be vigilant for the development of acute complications, including cerebral edema and status epilepticus, as well as chron

SUBMITTER: Bradshaw MJ 

PROVIDER: S-EPMC4965403 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature