Ontology highlight
ABSTRACT:
SUBMITTER: Konradt C
PROVIDER: S-EPMC4966557 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Nature microbiology 20160215
An important function of the blood-brain barrier is to exclude pathogens from the central nervous system, but some microorganisms benefit from the ability to enter this site. It has been proposed that Toxoplasma gondii can cross biological barriers as a motile extracellular form that uses transcellular or paracellular migration, or by infecting a host cell that then crosses the blood-brain barrier. Unexpectedly, analysis of acutely infected mice revealed significant numbers of free parasites in ...[more]