Respiratory weakness after mechanical ventilation is associated with one-year mortality - a prospective study.

ABSTRACT:

Background

Diaphragm dysfunction in mechanically ventilated patients is associated with poor outcome. Maximal inspiratory pressure (MIP) can be used to evaluate inspiratory muscle function. However, it is unclear whether respiratory weakness is independently associated with long-term mortality. The aim of this study was to determine if low MIP is independently associated with one-year mortality.

Methods

We conducted a prospective observational cohort study in an 18-bed ICU. Adults requiring at least 24 hours of mechanical ventilation with scheduled extubation and no evidence of pre-existing muscle weakness underwent MIP evaluation just before extubation. Patients were divided into two groups: low MIP (MIP ≤30 cmH2O) and high MIP (MIP >30 cmH2O). Mortality was recorded for on

SUBMITTER: Medrinal C 

PROVIDER: S-EPMC4967510 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature