Late Ebola virus relapse causing meningoencephalitis: a case report.

ABSTRACT:

Background

There are thousands of survivors of the 2014 Ebola outbreak in west Africa. Ebola virus can persist in survivors for months in immune-privileged sites; however, viral relapse causing life-threatening and potentially transmissible disease has not been described. We report a case of late relapse in a patient who had been treated for severe Ebola virus disease with high viral load (peak cycle threshold value 13.2).

Methods

A 39-year-old female nurse from Scotland, who had assisted the humanitarian effort in Sierra Leone, had received intensive supportive treatment and experimental antiviral therapies, and had been discharged with undetectable Ebola virus RNA in peripheral blood. The patient was readmitted to hospital 9 months after discharge with symptoms of acute me

SUBMITTER: Jacobs M 

PROVIDER: S-EPMC4967715 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature