Principal components of electrocortical activity during self-evaluation indicate depressive symptom severity.

ABSTRACT: Negative self-evaluation is an important psychological characteristic of depression. In order to study the underlying neural mechanisms, we examined event-related potentials (ERPs) during a self-evaluation task in a community sample (N = 150) of adults reporting a range of depressive symptoms. Principal components analysis (PCA) was used to separate processes that overlap in the average ERP, and neural source analysis was applied to localize the ERP components, with a particular focus on the frontal networks that are thought to be critical to affective self-regulation in depression. Consistent with previous research, individuals reporting greater depression showed enhanced negativity over medial frontal regions as well as attenuation of the late positive potential over parietal regions. Ex

SUBMITTER: Waters AC 

PROVIDER: S-EPMC4967808 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature