Endoscopic detection of cancer with lensless radioluminescence imaging and machine vision.

ABSTRACT: Complete removal of residual tumor tissue during surgical resection improves patient outcomes. However, it is often difficult for surgeons to delineate the tumor beyond its visible boundary. This has led to the development of intraoperative detectors that can image radiotracers accumulated within tumors, thus facilitating the removal of residual tumor tissue during surgical procedures. We introduce a beta imaging system that converts the beta radiation from the radiotracer into photons close to the decay origin through a CdWO4 scintillator and does not use any optical elements. The signal is relayed onto an EMCCD chip through a wound imaging fiber. The sensitivity of the device allows imaging of activity down to 100 nCi and the system has a resolution of at least 500 μm with a field of vie

SUBMITTER: Turkcan S 

PROVIDER: S-EPMC4967900 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature