Greater early and mid-pregnancy gestational weight gains are associated with excess adiposity in mid-childhood.

ABSTRACT:

Objective

It is unclear how specific periods of gestational weight gain (GWG) during pregnancy relate to childhood adiposity. The goal of this study was to assess the differential impact of GWG timing on childhood body composition.

Methods

In 979 mother-child pairs from the pre-birth Project Viva cohort, trimester-specific GWG was calculated using clinically recorded weights. Outcomes included body mass index (BMI) z-score, dual X-ray absorptiometry fat mass index (kg/m(2) ), and fat-free mass index (kg/m(2) ) in mid-childhood. Linear regression models were used to assess associations of each trimester's GWG (per 0.2 kg/week) with childhood outcomes, adjusted for maternal prepregnancy BMI, sociodemographic variables, lifestyle, and GWG in prior trimester(s).

Results

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SUBMITTER: Hivert MF 

PROVIDER: S-EPMC4968400 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature