MetLab: An In Silico Experimental Design, Simulation and Analysis Tool for Viral Metagenomics Studies.

ABSTRACT: Metagenomics, the sequence characterization of all genomes within a sample, is widely used as a virus discovery tool as well as a tool to study viral diversity of animals. Metagenomics can be considered to have three main steps; sample collection and preparation, sequencing and finally bioinformatics. Bioinformatic analysis of metagenomic datasets is in itself a complex process, involving few standardized methodologies, thereby hampering comparison of metagenomics studies between research groups. In this publication the new bioinformatics framework MetLab is presented, aimed at providing scientists with an integrated tool for experimental design and analysis of viral metagenomes. MetLab provides support in designing the metagenomics experiment by estimating the sequencing depth needed for

SUBMITTER: Norling M 

PROVIDER: S-EPMC4968819 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature