Regression Analysis of Optical Coherence Tomography Disc Variables for Glaucoma Diagnosis.

ABSTRACT:

Purpose

To report diagnostic accuracy of optical coherence tomography (OCT) disc variables using both time-domain (TD) and Fourier-domain (FD) OCT, and to improve the use of OCT disc variable measurements for glaucoma diagnosis through regression analyses that adjust for optic disc size and axial length-based magnification error.

Design

Observational, cross-sectional.

Participants

In total, 180 normal eyes of 112 participants and 180 eyes of 138 participants with perimetric glaucoma from the Advanced Imaging for Glaucoma Study.

Methods

Diagnostic variables evaluated from TD-OCT and FD-OCT were: disc area, rim area, rim volume, optic nerve head volume, vertical cup-to-disc ratio (CDR), and horizontal CDR. These were compared with overall retinal nerve fiber laye

SUBMITTER: Richter GM 

PROVIDER: S-EPMC4969235 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature