Fluorescent vinblastine probes for live cell imaging.

ABSTRACT: Herein we describe the synthesis of several fluorescent analogues of the clinically approved microtubule destabilizing agent vinblastine. The evaluated probes are the most potent described and provides the first example of uptake, distribution and live cell imaging using this well known antimitotic agent.

SUBMITTER: Meimetis LG 

PROVIDER: S-EPMC4970878 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature