Leptospira Seroprevalence and Risk Factors in Health Centre Patients in Hoima District, Western Uganda.

ABSTRACT:

Background

The burden of human leptospirosis in Uganda is unknown. We estimated the seroprevalence of Leptospira antibodies, probable acute/recent leptospirosis, and risk factors for seropositivity in humans in rural Western Uganda.

Methodology and principal findings

359 non-pregnant adults visiting the Kikuube and Kigorobya Health Centers were sequentially recruited during March and April 2014. A health history survey and serum were collected from consented participants. Overall, 69% reported having fever in the past year, with 49% reporting malaria, 14% malaria relapse, 6% typhoid fever, 3% brucellosis, and 0% leptospirosis. We tested sera by microscopic agglutination test (MAT) against eight Leptospira serovars representing seven serogroups. Leptospira seroprevalence was

SUBMITTER: Dreyfus A 

PROVIDER: S-EPMC4972303 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature