Global DNA Methylation Changes in Nile Tilapia Gonads during High Temperature-Induced Masculinization.

ABSTRACT: In some fish species, high or low temperature can switch the sex determination mechanisms and induce fish sex reversal when the gonads are undifferentiated. During this high or low temperature-induced sex reversal, the expressions of many genes are altered. However, genome-wide DNA methylation changes in fish gonads after high or low temperature treatment are unclear. Herein, we compared the global DNA methylation changes in the gonads from control females (CF), control males (CM), high temperature-treated females (TF), and high temperature-induced males (IM) from the F8 family of Nile tilapia (Oreochromis niloticus) using methylated DNA immunoprecipitation sequencing. The DNA methylation level in CF was higher than that in CM for various chromosomes. Both females and males showed an incre

SUBMITTER: Sun LX 

PROVIDER: S-EPMC4972363 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature