The role of liver-directed surgery in patients with hepatic metastasis from primary breast cancer: a multi-institutional analysis.

ABSTRACT:

Background

Data on surgical management of breast liver metastasis are limited. We sought to determine the safety and long-term outcome of patients undergoing hepatic resection of breast cancer liver metastases (BCLM).

Methods

Using a multi-institutional, international database, 131 patients who underwent surgery for BCLM between 1980 and 2014 were identified. Clinicopathologic and outcome data were collected and analyzed.

Results

Median tumor size of the primary breast cancer was 2.5 cm (IQR: 2.0-3.2); 58 (59.8%) patients had primary tumor nodal metastasis. The median time from diagnosis of breast cancer to metastasectomy was 34 months (IQR: 16.8-61.3). The mean size of the largest liver lesion was 3.0 cm (2.0-5.0); half of patients (52.0%) had a solitary metastasis.

SUBMITTER: Margonis GA 

PROVIDER: S-EPMC4972375 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature