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Draft Genome Sequence of a Metronidazole-Resistant Derivative of Gardnerella vaginalis Strain ATCC 14019.

ABSTRACT: We report the genome sequence of a metronidazole-resistant derivative of Gardnerella vaginalis ATCC 14019. This strain was obtained after serial selection to increase the MIC from 4 to ?500 µg/ml. Two coding changes, in genes encoding a response regulator and an NAD(+) synthetase, arose during selection.

SUBMITTER: Schuyler JA 

PROVIDER: S-EPMC4972788 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature

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Draft Genome Sequence of a Metronidazole-Resistant Derivative of Gardnerella vaginalis Strain ATCC 14019.

Schuyler Jessica A JA   Mordechai Eli E   Adelson Martin E ME   Gygax Scott E SE   Hilbert David W DW  

Genome announcements 20151112 6

We report the genome sequence of a metronidazole-resistant derivative of Gardnerella vaginalis ATCC 14019. This strain was obtained after serial selection to increase the MIC from 4 to ≥500 µg/ml. Two coding changes, in genes encoding a response regulator and an NAD(+) synthetase, arose during selection. ...[more]

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