Performance Improvement of the Goertzel Algorithm in Estimating of Protein Coding Regions Using Modified Anti-notch Filter and Linear Predictive Coding Model.

ABSTRACT: The aim of this paper is to improve the performance of the conventional Goertzel algorithm in determining the protein coding regions in deoxyribonucleic acid (DNA) sequences. First, the symbolic DNA sequences are converted into numerical signals using electron ion interaction potential method. Then by combining the modified anti-notch filter and linear predictive coding model, we proposed an efficient algorithm to achieve the performance improvement in the Goertzel algorithm for estimating genetic regions. Finally, a thresholding method is applied to precisely identify the exon and intron regions. The proposed algorithm is applied to several genes, including genes available in databases BG570 and HMR195 and the results are compared to other methods based on the nucleotide level evaluation

SUBMITTER: Farsani MS 

PROVIDER: S-EPMC4973456 | biostudies-literature | 2016 Jul-Sep

REPOSITORIES: biostudies-literature