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Relationship between automated total nucleated cell count and enumeration of cells on direct smears of canine synovial fluid.


ABSTRACT: Canine osteoarthritis is a common disorder seen in veterinary clinical practice and causes considerable morbidity in dogs as they age. Synovial fluid analysis is an important tool for diagnosis and treatment of canine joint disease and obtaining a total nucleated cell count (TNCC) is particularly important. However, the low sample volumes obtained during arthrocentesis are often insufficient for performing an automated TNCC, thereby limiting diagnostic interpretation. The aim of the present study was to investigate whether estimation of TNCC in canine synovial fluid could be achieved by performing manual cell counts on direct smears of fluid. Fifty-eight synovial fluid samples, taken by arthrocentesis from 48 dogs, were included in the study. Direct smears of synovial fluid were prepared,

SUBMITTER: Dusick A 

PROVIDER: S-EPMC4973857 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature