Patterns of diaphragm function in critically ill patients receiving prolonged mechanical ventilation: a prospective longitudinal study.

ABSTRACT:

Background

In intensive care unit (ICU) patients, diaphragmatic dysfunction (DD) can occur on admission or during the subsequent stay. The respective incidence of these two phenomena has not been previously studied in humans. The study was designed to describe temporal trends in diaphragm function in mechanically ventilated (MV) patients.

Methods

Ancillary study of a prospective, 6-month, observational cohort study conducted in two ICUs. MV patients were studied within 24 h following intubation (day-1) and every 48-72 h thereafter. Diaphragm function was assessed by twitch tracheal pressure (Ptr,stim) in response to bilateral anterior magnetic phrenic nerve stimulation. Diaphragm dysfunction was defined as Ptr,stim < 11 cmH2O. Patients who received MV for at least 5 days wer

SUBMITTER: Demoule A 

PROVIDER: S-EPMC4974210 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature