Novel correlates between antimullerian hormone and menstrual cycle characteristics in African-American women (23-35 years-old).

ABSTRACT:

Objective

To characterize normative antimüllerian hormone (AMH) levels and ascertain which factors are associated with AMH in a large cohort of reproductive-age women.

Design

Cross-sectional study.

Setting

Not applicable.

Patient(s)

A total of 1,654 African-American women (AAW) ages 23-34 at recruitment.

Intervention(s)

Not applicable.

Main outcome measure(s)

Serum AMH measured using an ultrasensitive ELISA.

Result(s)

The median AMH was 3.18 ng/mL, and there was a significant, but nonlinear, relationship between age and AMH, with levels peaking at age 25. As AMH was not normally distributed, log transformation was performed and used for all analyses. In a multivariable age-adjusted model, body mass index, current use of hormonal contracepti

SUBMITTER: Marsh EE 

PROVIDER: S-EPMC4975664 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature