Quantile Regression Analysis of the Distributional Effects of Air Pollution on Blood Pressure, Heart Rate Variability, Blood Lipids, and Biomarkers of Inflammation in Elderly American Men: The Normative Aging Study.

ABSTRACT:

Background

Previous studies have observed associations between air pollution and heart disease. Susceptibility to air pollution effects has been examined mostly with a test of effect modification, but little evidence is available whether air pollution distorts cardiovascular risk factor distribution.

Objectives

This paper aims to examine distributional and heterogeneous effects of air pollution on known cardiovascular biomarkers.

Methods

A total of 1,112 men from the Normative Aging Study and residents of the greater Boston, Massachusetts, area with mean age of 69 years at baseline were included in this study during the period 1995-2013. We used quantile regression and random slope models to investigate distributional effects and heterogeneity in the traffic-related r

SUBMITTER: Bind MA 

PROVIDER: S-EPMC4977045 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature