Prioritizing Environmental Chemicals for Obesity and Diabetes Outcomes Research: A Screening Approach Using ToxCast™ High-Throughput Data.

ABSTRACT:

Background

Diabetes and obesity are major threats to public health in the United States and abroad. Understanding the role that chemicals in our environment play in the development of these conditions is an emerging issue in environmental health, although identifying and prioritizing chemicals for testing beyond those already implicated in the literature is challenging. This review is intended to help researchers generate hypotheses about chemicals that may contribute to diabetes and to obesity-related health outcomes by summarizing relevant findings from the U.S. Environmental Protection Agency (EPA) ToxCast™ high-throughput screening (HTS) program.

Objectives

Our aim was to develop new hypotheses around environmental chemicals of potential interest for diabetes- or obesity

SUBMITTER: Auerbach S 

PROVIDER: S-EPMC4977057 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature