A new saccadic indicator of peripheral vestibular function based on the video head impulse test.

ABSTRACT:

Objective

While compensatory saccades indicate vestibular loss in the conventional head impulse test paradigm (HIMP), in which the participant fixates an earth-fixed target, we investigated a complementary suppression head impulse paradigm (SHIMP), in which the participant is fixating a head-fixed target to elicit anticompensatory saccades as a sign of vestibular function.

Methods

HIMP and SHIMP eye movement responses were measured with the horizontal video head impulse test in patients with unilateral vestibular loss, patients with bilateral vestibular loss, and in healthy controls.

Results

Vestibulo-ocular reflex gains showed close correlation (R(2) = 0.97) with slightly lower SHIMP than HIMP gains (mean gain difference 0.06 ± 0.05 SD, p < 0.001). However, the 2 par

SUBMITTER: MacDougall HG 

PROVIDER: S-EPMC4977115 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature