Polymyxin-B hemoperfusion in septic patients: analysis of a multicenter registry.

ABSTRACT:

Background

In 2010, the EUPHAS 2 collaborative group created a registry with the purpose of recording data from critically ill patients suffering from severe sepsis and septic shock treated with polymyxin-B hemoperfusion (PMX-HP) for endotoxin removal. The aim of the registry was to verify the application of PMX-HP in the daily clinical practice.

Methods

The EUPHAS 2 registry involved 57 centers between January 2010 and December 2014, collecting retrospective data of 357 patients (297 in Europe and 60 in Asia) suffering from severe sepsis and septic shock caused by proved or suspected infection related to Gram negative bacteria. All patients received atleast one cycle of extracorporeal endotoxin removal by PMX-HP.

Results

Septic shock was diagnosed in 305 (85.4 %) pat

SUBMITTER: Cutuli SL 

PROVIDER: S-EPMC4977232 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature