Prediabetes and Diabetes Are Associated With Arterial Stiffness in Older Adults: The ARIC Study.

ABSTRACT:

Background

To determine whether prediabetes and diabetes in older adults are associated with arterial stiffness measured in central and peripheral arteries and to examine characteristics that modify these associations.

Methods

Cohort members attending the 5th exam (2011-2013) of the Atherosclerosis Risk in Communities (ARIC) study had pulse wave velocity (PWV) measures performed at the carotid-femoral (cfPWV), brachial-ankle (baPWV), and femoral-ankle (faPWV) segments. Fasting glucose ≥126mg/dl, glycated hemoglobin (HbA1c) ≥6.5%, or currently taking diabetes medication defined diabetes. Fasting glucose 100-125mg/dl or HbA1c 5.7%-6.4% among those without diabetes defined prediabetes. Cross-sectional associations were modeled using multivariable linear regression.

Results</

SUBMITTER: Loehr LR 

PROVIDER: S-EPMC4978227 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature