Atherosclerosis and arterial stiffness in obstructive sleep apnea--a cardiovascular magnetic resonance study.

ABSTRACT:

Objective

Obstructive sleep apnoea (OSA) has been linked to cardiovascular risk factors, such as hypertension, and clinical cardiovascular endpoints. Our aim was to assess whether OSA is independently associated with atherosclerosis and vascular dysfunction as assessed by cardiovascular magnetic resonance (CMR).

Methods

58 patients with OSA and 39 matched control subjects without OSA underwent CMR of the aorta and carotid arteries. Carotid and aortic wall thickness and aortic distensibility were measured. Multi-weighted, high resolution CMR imaging was used for carotid atheroma characterization according to the American Heart Association (AHA) atheroma classification, modified for CMR.

Results

Carotid [1.47±0.03 mm vs. 1.26±0.05 mm, (P<0.01)] and aortic wall thickness

SUBMITTER: Kylintireas I 

PROVIDER: S-EPMC4978311 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature