Management of Patients With Pancreatic Cysts: Analysis of Possible False-Negative Cases of Malignancy.

ABSTRACT:

Goals

To examine the utility of integrated molecular pathology (IMP) in managing surveillance of pancreatic cysts based on outcomes and analysis of false negatives (FNs) from a previously published cohort (n=492).

Background

In endoscopic ultrasound with fine-needle aspiration (EUS-FNA) of cyst fluid lacking malignant cytology, IMP demonstrated better risk stratification for malignancy at approximately 3 years' follow-up than International Consensus Guideline (Fukuoka) 2012 management recommendations in such cases.

Study

Patient outcomes and clinical features of Fukuoka and IMP FN cases were reviewed. Practical guidance for appropriate surveillance intervals and surgery decisions using IMP were derived from follow-up data, considering EUS-FNA sampling limitations and

SUBMITTER: Kowalski T 

PROVIDER: S-EPMC4978609 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature